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A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin.
Zhang, Ruijie; Yang, Xiaozhi; Roque, Dana M; Li, Chenglong; Lin, Jiayuh.
Afiliación
  • Zhang R; Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
  • Yang X; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
  • Roque DM; Department of Medicinal Chemistry, College of Pharmacy, The University of Florida, Gainesville, Florida, United States of America.
  • Li C; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
  • Lin J; Department of Medicinal Chemistry, College of Pharmacy, The University of Florida, Gainesville, Florida, United States of America.
PLoS One ; 16(4): e0240145, 2021.
Article en En | MEDLINE | ID: mdl-33909625
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Sulfonamidas / Transducción de Señal / Antraquinonas / Cisplatino / Paclitaxel / Factor de Transcripción STAT3 / Proteínas de Neoplasias Límite: Female / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Sulfonamidas / Transducción de Señal / Antraquinonas / Cisplatino / Paclitaxel / Factor de Transcripción STAT3 / Proteínas de Neoplasias Límite: Female / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article