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Access to 2-arylquinazolines via catabolism/reconstruction of amino acids with the insertion of dimethyl sulfoxide.
Ma, Jin-Tian; Wang, Li-Sheng; Chai, Zhi; Chen, Xin-Feng; Tang, Bo-Cheng; Chen, Xiang-Long; He, Cai; Wu, Yan-Dong; Wu, An-Xin.
Afiliación
  • Ma JT; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • Wang LS; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • Chai Z; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • Chen XF; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • Tang BC; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • Chen XL; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • He C; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • Wu YD; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
  • Wu AX; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
Chem Commun (Camb) ; 57(44): 5414-5417, 2021 Jun 01.
Article en En | MEDLINE | ID: mdl-33949486
Quinazoline skeletons are synthesized by amino acid catabolism/reconstruction combined with the insertion/cyclization of dimethyl sulfoxide for the first time. The amino acid acts as a carbon and nitrogen source through HI-mediated catabolism and is then reconstructed using aromatic amines and dimethyl sulfoxide (DMSO) as a one-carbon synthon. This protocol is of great significance for the further study of the conversion of amino acids.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinazolinas / Dimetilsulfóxido / Aminoácidos Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinazolinas / Dimetilsulfóxido / Aminoácidos Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article