Cost-effectiveness of bariatric surgery versus community weight management to treat obesity-related idiopathic intracranial hypertension: evidence from a single-payer healthcare system.
Surg Obes Relat Dis
; 17(7): 1310-1316, 2021 Jul.
Article
en En
| MEDLINE
| ID: mdl-33952427
ABSTRACT
BACKGROUND:
Idiopathic intracranial hypertension (IIH) is associated with significant morbidity, predominantly affecting women of childbearing age living with obesity. Weight loss has demonstrated successful disease-modifying effects; however, the long-term cost-effectiveness of weight loss interventions for the treatment of IIH has not yet been established.OBJECTIVES:
To estimate the cost-effectiveness of weight-loss treatments for IIH.SETTING:
Single-payer healthcare system (National Health Service, England).METHODS:
A Markov model was developed comparing bariatric surgery with a community weight management intervention over 5-, 10-, and 20-year time horizons. Transition probabilities, utilities, and resource use were informed by the IIH Weight Trial (IIHWT), alongside the published literature. A probabilistic sensitivity analysis was conducted to characterize uncertainty within the model.RESULTS:
In the base case analysis, over a 20-year time horizon, bariatric surgery was "dominant," led to cost savings of £49,500, and generated an additional 1.16 quality-adjusted life years in comparison to the community weight management intervention. The probabilistic sensitivity analysis indicated a probability of 98% that bariatric surgery is the dominant option in terms of cost-effectiveness.CONCLUSION:
This economic modeling study has shown that when compared to community weight management, bariatric surgery is a highly cost-effective treatment option for IIH in women living with obesity. The model shows that surgery leads to long-term cost savings and health benefits, but that these do not occur until after 5 years post surgery, and then gradually increase over time.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Seudotumor Cerebral
/
Cirugía Bariátrica
Tipo de estudio:
Evaluation_studies
/
Health_economic_evaluation
Aspecto:
Patient_preference
Límite:
Female
/
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Surg Obes Relat Dis
Asunto de la revista:
METABOLISMO
Año:
2021
Tipo del documento:
Article
País de afiliación:
Reino Unido