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Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells.
Qian, Xing-Kai; Zhang, Jing; Song, Pei-Fang; Zhao, Yi-Su; Ma, Hong-Ying; Jin, Qiang; Wang, Dan-Dan; Guan, Xiao-Qing; Li, Shi-Yang; Bao, XiaoZe; Zou, Li-Wei.
Afiliación
  • Qian XK; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Zhang J; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Song PF; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Zhao YS; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Ma HY; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Jin Q; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Wang DD; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Guan XQ; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Li SY; Analytical Central Laboratory, Shengyang Harmony Health Medical Laboratory Co Ltd, 19 Wen Hui Road Shenyang 210112, China.
  • Bao X; College of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: baoxiaoze@zjut.edu.cn.
  • Zou LW; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: chemzlw@163.com.
Bioorg Med Chem ; 40: 116187, 2021 06 15.
Article en En | MEDLINE | ID: mdl-33965840
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carboxilesterasa / Pirazolonas / Inhibidores Enzimáticos / Adipogénesis / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carboxilesterasa / Pirazolonas / Inhibidores Enzimáticos / Adipogénesis / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China