Design and synthesis of gene-directed caged cyclic nucleotides exhibiting cell type selectivity.
Chem Commun (Camb)
; 57(46): 5630-5633, 2021 Jun 08.
Article
en En
| MEDLINE
| ID: mdl-34018507
ABSTRACT
We designed a new caging group that can be photoactivated only in the presence of a non-endogenous enzyme when exposed to 405 nm light. Because cells or tissues can be genetically tagged by an exogenously expressed enzyme, this novel method can serve as a strategy for adding targeting abilities to photocaged compounds.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Nucleótidos Cíclicos
Límite:
Humans
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Japón