Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways.
Comput Struct Biotechnol J
; 19: 2881-2890, 2021.
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| ID: mdl-34093999
7-AAD, 7-amino-actinomycin D; Apoptosis; Bax, Bcl-2 Associated X; Bcl-2, B cell lymphoma-2; Breast cancer; Chemoprevention; EGFR, Epidermal growth factor receptor; ERK, Extracellular-signal-regulated kinase; ErbB2, erythroblastic oncogene B; FBS, Fetal bovine serum; FITC, Fluorescein isothiocyanate; GAPDH, Glyceraldehyde 3-phosphate dehydrogenase; HER2-positive; JNK, c-Jun N-terminal kinase; PAMAMs; PAMAMs, poly(amidoamine) dendrimers; PE, Phycoerythrin; PVDF, Polyvinylidene difluoride
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