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Percutaneous Coronary Intervention for Chronic Total Occlusion in Single Coronary Arteries.
Choi, Jah Yeon; Rha, Seung-Woon; Choi, Byoung Geol; Choi, Se Yeon; Byun, Jae Kyeong; Jang, Won Young; Kim, Woohyeun; Na, Jin Oh; Choi, Cheol Ung; Kim, Eung Ju; Park, Chang Gyu; Seo, Hong Seog.
Afiliación
  • Choi JY; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Rha SW; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Choi BG; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Choi SY; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Byun JK; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Jang WY; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Kim W; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Na JO; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Choi CU; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Kim EJ; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Park CG; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
  • Seo HS; Cardiovascular Center, Korea University Guro Hospital, Seoul, Republic of Korea.
Tex Heart Inst J ; 48(2)2021 06 10.
Article en En | MEDLINE | ID: mdl-34111277
We retrospectively compared the results of percutaneous coronary intervention (PCI) and optimal medical therapy (OMT) for chronic total occlusion (CTO) in single coronary arteries to determine whether outcomes depend on the artery involved. From January 2004 through November 2015, a total of 731 patients were treated at our center for CTO in the left anterior descending coronary artery (LAD) (234 patients, 32%), left circumflex coronary artery (LCx) (184, 25.2%), or right coronary artery (RCA) (313, 42.8%). We further classified patients by treatment (PCI or OMT) and compared the cumulative incidence of major adverse cardiac events (MACE) and the composite of total death or myocardial infarction, as well as change in left ventricular ejection fraction from baseline. The 5-year cumulative incidence of MACE was similar between the treatment groups regardless of target vessel. The 5-year cumulative incidence of the composite of total death or myocardial infarction was significantly lower after PCI than after OMT or failed PCI in the LCx (2.6% vs 11.5%; P=0.020; log-rank) and RCA (5.8% vs 17.2%; P=0.002) groups, but not in the LAD group. Cox proportional hazards regression analysis indicated that PCI independently predicted a lower incidence of the composite of total death or myocardial infarction in the LCx group (hazard ratio [HR]=0.184; 95% CI, 0.0035-0.972; P=0.046) and the RCA group (HR=0.316; 95% CI, 0.119-0.839; P=0.021). The artery involved does not appear to affect clinical outcomes of successful PCI for single-vessel CTO. Further investigation in a randomized clinical trial is warranted.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_cardiovascular_diseases / 6_ischemic_heart_disease Asunto principal: Oclusión Coronaria / Intervención Coronaria Percutánea Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Tex Heart Inst J Año: 2021 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_cardiovascular_diseases / 6_ischemic_heart_disease Asunto principal: Oclusión Coronaria / Intervención Coronaria Percutánea Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Tex Heart Inst J Año: 2021 Tipo del documento: Article
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