Malignancy-induced hemophagocytic lymphohistiocytosis in a case of signet ring cell carcinoma of the stomach.
Indian J Pathol Microbiol
; 64(Supplement): S85-S88, 2021 Jun.
Article
en En
| MEDLINE
| ID: mdl-34135144
ABSTRACT
Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially life-threatening condition associated with high mortality and can be classified into primary (familial) and secondary HLH. Primary HLH is an inherited, autosomal recessive disorder associated with defects in perforin function, whereas secondary HLH is associated with infections, especially Epstein-Barr virus infection, malignancies, and autoimmune disorders. Patients with malignancy-associated secondary HLH experience symptoms that overlap with those described for other HLH types, which is associated with an increased incidence of misdiagnosis and mortality. Here, we report the case of a patient with secondary HLH associated with a solid malignancy (signet-ring cell carcinoma of the stomach).
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estómago
/
Neoplasias Gástricas
/
Carcinoma de Células en Anillo de Sello
/
Linfohistiocitosis Hemofagocítica
Tipo de estudio:
Etiology_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Indian J Pathol Microbiol
Año:
2021
Tipo del documento:
Article
País de afiliación:
India