ALSUntangled #62: vitamin C.

Bedlack, Richard; Barkhaus, Paul; Carter, Greg; Crayle, Jesse; Mcdermott, Christopher; Pattee, Gary; Polak, Meraida; Salmon, Kristiana; Wicks, Paul

Bedlack, Richard; Barkhaus, Paul; Carter, Greg; Crayle, Jesse; Mcdermott, Christopher; Pattee, Gary; Polak, Meraida; Salmon, Kristiana; Wicks, Paul.

Afiliación

Bedlack R; Department of Neurology, Duke University, Durham, NC, USA.
Barkhaus P; Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Carter G; Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.
Crayle J; Department of Neurology, Washington University in St Louis School of Medicine, St Louis, MO, USA.
Mcdermott C; Department of Neuroscience, The University of Sheffield Institute for Translational Neuroscience, Sheffield, United Kingdom of Great Britain and Northern Ireland.
Pattee G; Department of Neurology, Neurology Associates, Lincoln, NE, USA.
Polak M; Department of Neurology, Emory Healthcare, Atlanta, GA, USA.
Salmon K; Department of Neurology, McGill Centre for Research in Neuroscience, Montreal, Canada.
Wicks P; UIndependent Consultant, United Kingdom of Great Britain and Northern Ireland.

Amyotroph Lateral Scler Frontotemporal Degener ; 23(5-6): 476-479, 2022 08.

Article en En | MEDLINE | ID: mdl-34187257

ABSTRACT

ABSTRACT

Vitamin C is one of the most common supplements taken by people with ALS. As an antioxidant, it has a plausible mechanism for slowing disease progression and there are some flawed pre-clinical studies and case reports suggesting benefit. However, a small human trial showed no benefit. Given this negative trial, we do not currently advise vitamin C as an ALS treatment.

Asunto(s)

Esclerosis Amiotrófica Lateral; Ácido Ascórbico; Vitaminas; Esclerosis Amiotrófica Lateral/tratamiento farmacológico; Ácido Ascórbico/uso terapéutico; Ensayos Clínicos como Asunto; Suplementos Dietéticos; Humanos; Resultado del Tratamiento; Vitaminas/uso terapéutico

Palabras clave

Vitamin C; acorbic acid; ascorbate; clinical trials; models; therapy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Ascórbico / Vitaminas / Esclerosis Amiotrófica Lateral Límite: Humans Idioma: En Revista: Amyotroph Lateral Scler Frontotemporal Degener Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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