ASC-1 transporter-dependent amino acid uptake is required for the efficient thermogenic response of human adipocytes to adrenergic stimulation.

Arianti, Rini; Vinnai, Boglárka Ágnes; Tóth, Beáta B; Shaw, Abhirup; Csosz, Éva; Vámos, Attila; Gyory, Ferenc; Fischer-Posovszky, Pamela; Wabitsch, Martin; Kristóf, Endre; Fésüs, László

Arianti, Rini; Vinnai, Boglárka Ágnes; Tóth, Beáta B; Shaw, Abhirup; Csosz, Éva; Vámos, Attila; Gyory, Ferenc; Fischer-Posovszky, Pamela; Wabitsch, Martin; Kristóf, Endre; Fésüs, László.

Afiliación

Arianti R; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary.
Vinnai BÁ; Doctoral School of Molecular Cell and Immune Biology, University of Debrecen, Hungary.
Tóth BB; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary.
Shaw A; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary.
Csosz É; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary.
Vámos A; Doctoral School of Molecular Cell and Immune Biology, University of Debrecen, Hungary.
Gyory F; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary.
Fischer-Posovszky P; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary.
Wabitsch M; Doctoral School of Molecular Cell and Immune Biology, University of Debrecen, Hungary.
Kristóf E; Department of Surgery, Faculty of Medicine, University of Debrecen, Hungary.
Fésüs L; Division of Pediatric Endocrinology and Diabetes, University Medical Center Ulm, Germany.

FEBS Lett ; 595(16): 2085-2098, 2021 08.

Article en En | MEDLINE | ID: mdl-34197627

Asunto(s)

Adipocitos/efectos de los fármacos; Adipocitos/metabolismo; Adrenérgicos/farmacología; Sistema de Transporte de Aminoácidos y+/metabolismo; Aminoácidos/metabolismo; Termogénesis; Transporte Biológico/efectos de los fármacos; Humanos; Termogénesis/efectos de los fármacos

Palabras clave

ASC-1 inhibition; adipocytes; gene expression; obesity; proton leak respiration; thermogenesis; uncoupling protein 1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adipocitos / Adrenérgicos / Termogénesis / Sistema de Transporte de Aminoácidos y/ / Aminoácidos Límite: Humans Idioma: En Revista: FEBS Lett Año: 2021 Tipo del documento: Article País de afiliación: Hungria

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