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Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens.
Lopes, Rui; Sprouffske, Kathleen; Sheng, Caibin; Uijttewaal, Esther C H; Wesdorp, Adriana Emma; Dahinden, Jan; Wengert, Simon; Diaz-Miyar, Juan; Yildiz, Umut; Bleu, Melusine; Apfel, Verena; Mermet-Meillon, Fanny; Krese, Rok; Eder, Mathias; Olsen, André Vidas; Hoppe, Philipp; Knehr, Judith; Carbone, Walter; Cuttat, Rachel; Waldt, Annick; Altorfer, Marc; Naumann, Ulrike; Weischenfeldt, Joachim; deWeck, Antoine; Kauffmann, Audrey; Roma, Guglielmo; Schübeler, Dirk; Galli, Giorgio G.
Afiliación
  • Lopes R; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland. rui.lopes@novartis.com giorgio.galli@novartis.com.
  • Sprouffske K; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Sheng C; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Uijttewaal ECH; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Wesdorp AE; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Dahinden J; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Wengert S; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Diaz-Miyar J; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Yildiz U; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Bleu M; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Apfel V; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Mermet-Meillon F; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Krese R; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Eder M; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Olsen AV; Biotech Research and Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Hoppe P; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Knehr J; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Carbone W; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Cuttat R; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Waldt A; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Altorfer M; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Naumann U; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Weischenfeldt J; Biotech Research and Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • deWeck A; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Kauffmann A; Disease area Oncology, Novartis Institute for Biomedical Research, CH-4002 Basel, Switzerland.
  • Roma G; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Schübeler D; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Galli GG; Faculty of Sciences, University of Basel, Basel, Switzerland.
Sci Adv ; 7(27)2021 07.
Article en En | MEDLINE | ID: mdl-34215580
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Redes Reguladoras de Genes / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas Límite: Humans Idioma: En Revista: Sci Adv Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Redes Reguladoras de Genes / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas Límite: Humans Idioma: En Revista: Sci Adv Año: 2021 Tipo del documento: Article