Shuttle-Shape Carrier-Free Platinum-Coordinated Nanoreactors with O<sub>2</sub> Self-Supply and ROS Augment for Enhanced Phototherapy of Hypoxic Tumor.

Fu, Xu; Yin, Wen; Shi, Dao; Yang, Yifan; He, Suisui; Hai, Jun; Hou, Zhenqing; Fan, Zhongxiong; Zhang, Dekui

Shuttle-Shape Carrier-Free Platinum-Coordinated Nanoreactors with O₂ Self-Supply and ROS Augment for Enhanced Phototherapy of Hypoxic Tumor.

Fu, Xu; Yin, Wen; Shi, Dao; Yang, Yifan; He, Suisui; Hai, Jun; Hou, Zhenqing; Fan, Zhongxiong; Zhang, Dekui.

Afiliación

Shi D; Department of Biomaterials, College of Materials, Research Center of Biomedical Engineering of Xiamen & Key Laboratory of Biomedical Engineering of Fujian Province & Fujian Provincial Key Laboratory for Soft Functional Materials Research, Xiamen University, Xiamen 361005, China.
Yang Y; Department of Biomaterials, College of Materials, Research Center of Biomedical Engineering of Xiamen & Key Laboratory of Biomedical Engineering of Fujian Province & Fujian Provincial Key Laboratory for Soft Functional Materials Research, Xiamen University, Xiamen 361005, China.
He S; State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University, Lanzhou 730000, Gansu, China.
Hai J; State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University, Lanzhou 730000, Gansu, China.
Hou Z; Department of Biomaterials, College of Materials, Research Center of Biomedical Engineering of Xiamen & Key Laboratory of Biomedical Engineering of Fujian Province & Fujian Provincial Key Laboratory for Soft Functional Materials Research, Xiamen University, Xiamen 361005, China.
Fan Z; Department of Biomaterials, College of Materials, Research Center of Biomedical Engineering of Xiamen & Key Laboratory of Biomedical Engineering of Fujian Province & Fujian Provincial Key Laboratory for Soft Functional Materials Research, Xiamen University, Xiamen 361005, China.

ACS Appl Mater Interfaces ; 13(28): 32690-32702, 2021 Jul 21.

Article en En | MEDLINE | ID: mdl-34229434

Asunto(s)

Antineoplásicos/uso terapéutico; Camptotecina/análogos & derivados; Portadores de Fármacos/química; Nanoestructuras/química; Neoplasias/tratamiento farmacológico; Hipoxia Tumoral/efectos de los fármacos; Animales; Antineoplásicos/química; Camptotecina/química; Camptotecina/uso terapéutico; Catálisis/efectos de la radiación; Línea Celular Tumoral; Portadores de Fármacos/efectos de la radiación; Liberación de Fármacos; Femenino; Humanos; Peróxido de Hidrógeno/química; Peróxido de Hidrógeno/metabolismo; Luz; Azul de Metileno/análogos & derivados; Azul de Metileno/efectos de la radiación; Ratones Endogámicos BALB C; Nanoestructuras/efectos de la radiación; Neoplasias/metabolismo; Oxígeno/metabolismo; Fármacos Fotosensibilizantes/química; Fármacos Fotosensibilizantes/uso terapéutico; Terapia Fototérmica; Platino (Metal)/química; Platino (Metal)/efectos de la radiación; Polímeros/síntesis química; Polímeros/química; Polímeros/efectos de la radiación; Porosidad; Oxígeno Singlete/metabolismo; Nanomedicina Teranóstica

Palabras clave

O2 self-supply; ROS augment; hypoxic tumor; nanoreactors; phototherapy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Camptotecina / Portadores de Fármacos / Nanoestructuras / Hipoxia Tumoral / Neoplasias / Antineoplásicos Tipo de estudio: Guideline Límite: Animals / Female / Humans Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2021 Tipo del documento: Article

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