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IFN-γ Drives Human Monocyte Differentiation into Highly Proinflammatory Macrophages That Resemble a Phenotype Relevant to Psoriasis.
Luque-Martin, Rosario; Angell, Davina C; Kalxdorf, Mathias; Bernard, Sharon; Thompson, William; Eberl, H Christian; Ashby, Charlotte; Freudenberg, Johannes; Sharp, Catriona; Van den Bossche, Jan; de Jonge, Wouter J; Rioja, Inmaculada; Prinjha, Rab K; Neele, Annette E; de Winther, Menno P J; Mander, Palwinder K.
Afiliación
  • Luque-Martin R; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Angell DC; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Kalxdorf M; Cellzome GmbH, GlaxoSmithKline, Heidelberg, Germany.
  • Bernard S; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Thompson W; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Eberl HC; Cellzome GmbH, GlaxoSmithKline, Heidelberg, Germany.
  • Ashby C; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Freudenberg J; Human Genetics, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Sharp C; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Van den Bossche J; Department of Molecular Cell Biology and Immunology, Amsterdam Cardiovascular Sciences, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; and.
  • de Jonge WJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Rioja I; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Prinjha RK; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom.
  • Neele AE; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • de Winther MPJ; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Mander PK; Immuno-Epigenetics, Adaptive Immunity Research Unit, GSK Medicines Research Centre, Stevenage, United Kingdom; palwinder.k.mander@gsk.com.
J Immunol ; 207(2): 555-568, 2021 07 15.
Article en En | MEDLINE | ID: mdl-34233910

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Psoriasis / Monocitos / Diferenciación Celular / Interferón gamma / Inflamación / Macrófagos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Immunol Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Psoriasis / Monocitos / Diferenciación Celular / Interferón gamma / Inflamación / Macrófagos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Immunol Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos
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