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Post Viral Olfactory Dysfunction After SARS-CoV-2 Infection: Anticipated Post-pandemic Clinical Challenge.
Kapoor, Dhruv; Verma, Neha; Gupta, Neelima; Goyal, Arun.
Afiliación
  • Kapoor D; Department of Otorhinolaryngology, University College of Medical Sciences, Delhi, India.
  • Verma N; Department of Otorhinolaryngology, University College of Medical Sciences, Delhi, India.
  • Gupta N; Present Address: Department of Otorhinolaryngology, Guru Teg Bahadur Hospital, Ward 25, Delhi, 110 095 India.
  • Goyal A; Department of Otorhinolaryngology, University College of Medical Sciences, Delhi, India.
Indian J Otolaryngol Head Neck Surg ; 74(Suppl 3): 4571-4578, 2022 Dec.
Article en En | MEDLINE | ID: mdl-34249668
ABSTRACT
Persistent olfactory dysfunction (OD) is the second most common symptom of post coronavirus disease-19 (COVID-19) now being termed long-COVID. Its prevalence after recovery from COVID-19 is estimated to be 12% after nearly 6 months of follow-up. It thus becomes imperative for the treating clinicians to update themselves with the pathophysiology of this post COVID disability as well as the tools for diagnosis and the available treatment options. A systematic literature search was performed as per PRISMA guidelines in MEDLINE, Cochrane Library, LILACS, Google Scholar, ClinicalTrials.gov, and medRxiv databases. The keywords used were covid-19, Olfactory Disorders, Smell, Anosmia, PVOD, Post Viral Olfactory Disorders, post-covid and post haul. All articles were studied for definition, mechanism, diagnostic tests and treatment options for post COVID OD. 33 published articles and 8 ongoing trials were found relevant and included after full-text review. SARS-CoV-2 can cause conductive, neural and central OD. Olfactory evaluation can be done both subjectively (visual analogue scale) and objectively (Sniffin' sticks, Sinonasal Outcome Test, University of Pennsylvania Smell Identification Test and modified Davidson's alcohol sniff test). They can be used to detect and follow-up patients. Despite several on-going clinical trials, the most reliable and advisable treatment option available till date is olfactory training.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Indian J Otolaryngol Head Neck Surg Año: 2022 Tipo del documento: Article País de afiliación: India

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Indian J Otolaryngol Head Neck Surg Año: 2022 Tipo del documento: Article País de afiliación: India
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