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Gut-Restricted Selective Cyclooxygenase-2 (COX-2) Inhibitors for Chemoprevention of Colorectal Cancer.
Zhang, Zhuming; Ghosh, Avijit; Connolly, Peter J; King, Peter; Wilde, Thomas; Wang, Jianyao; Dong, Yawei; Li, Xueliang; Liao, Daohong; Chen, Hao; Tian, Gaochao; Suarez, Javier; Bonnette, William G; Pande, Vineet; Diloreto, Karen A; Shi, Yifan; Patel, Shefali; Pietrak, Beth; Szewczuk, Lawrence; Sensenhauser, Carlo; Dallas, Shannon; Edwards, James P; Bachman, Kurtis E; Evans, David C.
Afiliación
  • Zhang Z; Discovery Chemistry, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Ghosh A; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Connolly PJ; Discovery Chemistry, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • King P; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Wilde T; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Wang J; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Dong Y; Chemistry, Pharmaron Beijing, Co. Ltd., No. 6, TaiHe Road, BDA Beijing 100176, P. R. China.
  • Li X; Chemistry, Pharmaron Beijing, Co. Ltd., No. 6, TaiHe Road, BDA Beijing 100176, P. R. China.
  • Liao D; Chemistry, Pharmaron Beijing, Co. Ltd., No. 6, TaiHe Road, BDA Beijing 100176, P. R. China.
  • Chen H; Chemistry, Pharmaron Beijing, Co. Ltd., No. 6, TaiHe Road, BDA Beijing 100176, P. R. China.
  • Tian G; Discovery Technology and Molecular Pharmacology, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Suarez J; Discovery Technology and Molecular Pharmacology, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Bonnette WG; Discovery Technology and Molecular Pharmacology, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Pande V; Discovery Chemistry, Janssen Research and Development, Turnhoutseweg 30, B-2340 Beerse, Belgium.
  • Diloreto KA; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Shi Y; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Patel S; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Pietrak B; Discovery Technology and Molecular Pharmacology, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Szewczuk L; Discovery Technology and Molecular Pharmacology, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Sensenhauser C; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Dallas S; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Edwards JP; Discovery Chemistry, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Bachman KE; Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
  • Evans DC; Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States.
J Med Chem ; 64(15): 11570-11596, 2021 08 12.
Article en En | MEDLINE | ID: mdl-34279934
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_colon_rectum_cancers Asunto principal: Neoplasias Colorrectales / Ciclooxigenasa 2 / Inhibidores de la Ciclooxigenasa 2 / Celecoxib / Etoricoxib / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_colon_rectum_cancers Asunto principal: Neoplasias Colorrectales / Ciclooxigenasa 2 / Inhibidores de la Ciclooxigenasa 2 / Celecoxib / Etoricoxib / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos