Nuclear Receptor Nur77 Protects Against Abdominal Aortic Aneurysm by Ameliorating Inflammation Via Suppressing LOX-1.

Zhang, Hengyuan; Geng, Na; Sun, Lingyue; Che, Xinyu; Xiao, Qingqing; Tao, Zhenyu; Chen, Long; Lyu, Yuyan; Shao, Qin; Pu, Jun

Zhang, Hengyuan; Geng, Na; Sun, Lingyue; Che, Xinyu; Xiao, Qingqing; Tao, Zhenyu; Chen, Long; Lyu, Yuyan; Shao, Qin; Pu, Jun.

Afiliación

Zhang H; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Geng N; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Sun L; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Che X; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Xiao Q; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Tao Z; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Chen L; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Lyu Y; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Shao Q; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.
Pu J; Department of Cardiology Renji HospitalSchool of Medicine, Shanghai Jiao Tong University Shanghai China.

J Am Heart Assoc ; 10(15): e021707, 2021 08 03.

Article en En | MEDLINE | ID: mdl-34325521

Asunto(s)

Aorta; Inflamación/metabolismo; Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares/metabolismo; Receptores Depuradores de Clase E/metabolismo; Animales; Aorta/inmunología; Aorta/patología; Aneurisma de la Aorta Abdominal/metabolismo; Citocinas/metabolismo; Descubrimiento de Drogas; Elastina/metabolismo; Humanos; Metaloproteinasa 9 de la Matriz/metabolismo; Ratones; Ratones Noqueados; Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares/deficiencia; Tamaño de los Órganos; Transducción de Señal; Remodelación Vascular/inmunología

Palabras clave

abdominal; angiotensin II; aortic aneurysm; inflammation; macrophage; nuclear receptor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aorta / Receptores Depuradores de Clase E / Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares / Inflamación Límite: Animals / Humans Idioma: En Revista: J Am Heart Assoc Año: 2021 Tipo del documento: Article

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