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MicroRNAs involve in bicuspid aortic aneurysm: pathogenesis and biomarkers.
Jia, Hao; Kang, Le; Ma, Zhen; Lu, Shuyang; Huang, Ben; Wang, Chunsheng; Zou, Yunzeng; Sun, Yongxin.
Afiliación
  • Jia H; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China.
  • Kang L; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China.
  • Ma Z; Central Laboratory of Cardiovascular Institute, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China.
  • Lu S; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China.
  • Huang B; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China.
  • Wang C; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China. wang.chunsheng@zs-hospital.sh.cn.
  • Zou Y; Central Laboratory of Cardiovascular Institute, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China. zou.yunzeng@zs-hospital.sh.cn.
  • Sun Y; Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 1069 Xietu Road, 200032, Shanghai, People's Republic of China. sun.yongxin@zs-hospital.sh.cn.
J Cardiothorac Surg ; 16(1): 230, 2021 Aug 12.
Article en En | MEDLINE | ID: mdl-34384454
ABSTRACT
The incidence of bicuspid aortic valves (BAV) is high in the whole population, BAV-related thoracic aortic aneurysm (TAA) is accompanied by many adverse vascular events. So far, there are two key points in dealing with BAV-related TAA. First is fully understanding on its pathogenesis. Second is optimizing surgical intervention time. This review aims to illustrate the potential role of miRNAs in both aspects, that is, how miRNAs are involved in the occurrence and progression of BAV-related TAA, and the feasibilities of miRNAs as biomarkers.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma de la Aorta Torácica / MicroARNs / Enfermedad de la Válvula Aórtica Bicúspide Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: J Cardiothorac Surg Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma de la Aorta Torácica / MicroARNs / Enfermedad de la Válvula Aórtica Bicúspide Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: J Cardiothorac Surg Año: 2021 Tipo del documento: Article