Acute Effects of Ibrutinib on Ventricular Arrhythmia in Spontaneously Hypertensive Rats.

Du, Beibei; Chakraborty, Praloy; Azam, Mohammed Ali; Massé, Stéphane; Lai, Patrick F H; Niri, Ahmed; Si, Daoyuan; Thavendiranathan, Paaladinesh; Abdel-Qadir, Husam; Billia, Filio; Nanthakumar, Kumaraswamy

Du, Beibei; Chakraborty, Praloy; Azam, Mohammed Ali; Massé, Stéphane; Lai, Patrick F H; Niri, Ahmed; Si, Daoyuan; Thavendiranathan, Paaladinesh; Abdel-Qadir, Husam; Billia, Filio; Nanthakumar, Kumaraswamy.

Afiliación

Du B; The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, Toronto, Ontario, Canada.
Chakraborty P; Department of Cardiology, The Third Hospital of Jilin University, Jilin Provincial Cardiovascular Research Institute, Changchun, China.
Azam MA; The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, Toronto, Ontario, Canada.
Massé S; The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, Toronto, Ontario, Canada.
Lai PFH; The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, Toronto, Ontario, Canada.
Niri A; The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, Toronto, Ontario, Canada.
Si D; The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, Toronto, Ontario, Canada.
Thavendiranathan P; The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, Toronto, Ontario, Canada.
Abdel-Qadir H; Department of Cardiology, The Third Hospital of Jilin University, Jilin Provincial Cardiovascular Research Institute, Changchun, China.
Billia F; Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Nanthakumar K; Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

JACC CardioOncol ; 2(4): 614-629, 2020 Nov.

Article en En | MEDLINE | ID: mdl-34396273

Palabras clave

AF, atrial fibrillation; AMPK, adenosine monophosphate-activated protein kinase; APD, action potential duration; CA, calcium alternans; CaMKII, Ca2+/calmodulin-dependent protein kinase II; CaT, calcium transient; CaTD, calcium transient duration; DAD, delayed afterdepolarization; EAD, early afterpolarization; LV, left ventricular; PI3K, phosphoinositide 3-kinase; PLB, phospholamban; SCaE, spontaneous calcium elevation; SHR, spontaneous hypertension rat; SR, sarcoplasmic reticulum; VA, ventricular arrhythmia; VF, ventricular fibrillation; action potential duration alternans; calcium handling; ibrutinib; spatial discordant repolarization; ventricular arrythmias

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline Idioma: En Revista: JACC CardioOncol Año: 2020 Tipo del documento: Article País de afiliación: Canadá

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