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Near Full-Length Genomic Characterization of Two Novel HIV-1 Unique Recombinant Forms (CRF01_AE/CRF07_BC) Among Men Who Have Sex with Men in Shijiazhuang City, Hebei Province, China.
Han, Leilei; Li, Hanping; Wang, Lijing; Jia, Lei; Han, Jingwan; Li, Tianyi; Wang, Xiaolin; Liu, Yongjian; Li, Jingyun; Lu, Jianhua; Qu, Xiaojing; He, Xuhui; Liu, Haichun; Li, Lin; Dai, Erhei.
Afiliación
  • Han L; School of Public Health, North China University of Science and Technology, Tangshan, China.
  • Li H; Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China.
  • Wang L; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Jia L; Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China.
  • Han J; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Li T; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Wang X; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Liu Y; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Li J; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Lu J; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
  • Qu X; Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China.
  • He X; Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China.
  • Liu H; Clinical Laboratory, The Second Hospital of Xingtai, Xingtai, China.
  • Li L; Clinical Laboratory, Zhangjiakou Infectious Disease Hospital, Zhangjiakou, China.
  • Dai E; State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
AIDS Res Hum Retroviruses ; 37(12): 978-984, 2021 12.
Article en En | MEDLINE | ID: mdl-34465138
ABSTRACT
Unique recombinant forms (URFs) are more likely developed among HIV-1 infections through men who have sex with men (MSM) because of cocirculation of multiple subtypes. In this study, two novel URFs deriving from two HIV-positive subjects (HB010014, HB010063) were identified in Shijiazhuang, Hebei province, China, and two sequences formed a distinct monophyletic cluster. Further recombination analysis showed that of two new URFs were consisted of circulating recombinant form (CRF)01_AE and CRF07_BC. The subregion phylogenetic analysis indicated that CRF01_AE segments were traced back to cluster 4 of CRF01_AE strains, which were prevalent among HIV-1 infections through MSM in China. New URFs being developing gradually and spreading released that more and more novel recombinant strains of HIV-1 could be developed, which means that the past prevention strategies need to be adjusted.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_enfermedades_transmissibles Asunto principal: Infecciones por VIH / VIH-1 / Minorías Sexuales y de Género Límite: Humans / Male País/Región como asunto: Asia Idioma: En Revista: AIDS Res Hum Retroviruses Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2021 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_enfermedades_transmissibles Asunto principal: Infecciones por VIH / VIH-1 / Minorías Sexuales y de Género Límite: Humans / Male País/Región como asunto: Asia Idioma: En Revista: AIDS Res Hum Retroviruses Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2021 Tipo del documento: Article País de afiliación: China