Methods for fabricating oxygen releasing biomaterials.
J Drug Target
; 30(2): 188-199, 2022 02.
Article
en En
| MEDLINE
| ID: mdl-34486908
ABSTRACT
Sustained external supply of oxygen (O2) to engineered tissue constructs is important for their survival in the body while angiogenesis is taking place. In the recent years, the trend towards the fabrication of various O2-generating materials that can provide prolonged and controlled O2 source to the large volume tissue constructs resulted in preventing necrosis associated with the lack of O2 supply. In this review, we explain different methods employed in the fabrication of O2-generating materials such as emulsion, microfluidics, solvent casting, freeze drying, electrospraying, gelation, microfluidic and three-dimensional (3D) bioprinting methods. After discussing pros and cons of each method, we review physical, chemical, and biological characterisation techniques used to analyse the resulting product. Finally, the challenges and future directions in the field are discussed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Materiales Biocompatibles
/
Bioimpresión
Idioma:
En
Revista:
J Drug Target
Asunto de la revista:
FARMACOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Turquía