Concurrent use of anlotinib overcomes acquired resistance to EGFR-TKI in patients with advanced EGFR-mutant non-small cell lung cancer.

Zhang, Chen; Cao, Honggang; Cui, Yanan; Jin, Shidai; Gao, Wen; Huang, Chenjun; Guo, Renhua

Zhang, Chen; Cao, Honggang; Cui, Yanan; Jin, Shidai; Gao, Wen; Huang, Chenjun; Guo, Renhua.

Afiliación

Zhang C; Department of Medical Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cao H; Department of Medical Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cui Y; Department of Medical Oncology, the Third People's Hospital of Yancheng, Yancheng, China.
Jin S; Department of Medical Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Gao W; Department of Medical Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Huang C; Department of Medical Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Guo R; Department of Cardiothoracic Surgery, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.

Thorac Cancer ; 12(19): 2574-2584, 2021 10.

Article en En | MEDLINE | ID: mdl-34510760

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Resistencia a Antineoplásicos/efectos de los fármacos; Gefitinib/farmacología; Indoles/farmacología; Neoplasias Pulmonares/tratamiento farmacológico; Inhibidores de Proteínas Quinasas/farmacología; Quinolinas/farmacología; Adulto; Anciano; Anciano de 80 o más Años; Animales; Apoptosis/efectos de los fármacos; Carcinoma de Pulmón de Células no Pequeñas/genética; Línea Celular Tumoral; Modelos Animales de Enfermedad; Regulación hacia Abajo; Quimioterapia Combinada; Receptores ErbB/genética; Femenino; Humanos; Neoplasias Pulmonares/genética; Masculino; Ratones; Ratones Endogámicos BALB C; Persona de Mediana Edad; Estudios Retrospectivos

Palabras clave

EGFR-TKI; VEGFR; acquired resistance; anlotinib; non-small cell lung cancer

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND / 4_TD / 6_ODS3_enfermedades_notrasmisibles Problema de salud: 3_diarrhea / 4_diarrhoeal_infections / 6_other_respiratory_diseases / 6_trachea_bronchus_lung_cancer Asunto principal: Quinolinas / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Gefitinib / Indoles / Neoplasias Pulmonares Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Thorac Cancer Año: 2021 Tipo del documento: Article País de afiliación: China

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