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Rational formulation engineering of fraxinellone utilizing 6-O-α-D-maltosyl-ß-cyclodextrin for enhanced oral bioavailability and hepatic fibrosis therapy.
Li, Jianbo; Feng, Tiange; Yang, Weijing; Xu, Yaru; Wang, Shuaishuai; Cai, Huijie; Liu, Zhilei; Qiang, Hong; Zhang, Jinjie.
Afiliación
  • Li J; Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
  • Feng T; Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
  • Yang W; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou, Henan, China.
  • Xu Y; Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
  • Wang S; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou, Henan, China.
  • Cai H; Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
  • Liu Z; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou, Henan, China.
  • Qiang H; Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
  • Zhang J; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou, Henan, China.
Drug Deliv ; 28(1): 1890-1902, 2021 Dec.
Article en En | MEDLINE | ID: mdl-34519225
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzofuranos / Ciclodextrinas / Composición de Medicamentos / Cirrosis Hepática / Maltosa Límite: Animals / Humans / Male Idioma: En Revista: Drug Deliv Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzofuranos / Ciclodextrinas / Composición de Medicamentos / Cirrosis Hepática / Maltosa Límite: Animals / Humans / Male Idioma: En Revista: Drug Deliv Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2021 Tipo del documento: Article País de afiliación: China