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Performance of qSOFA, SIRS, and the qSOFA + SIRS combinations for predicting 30-day adverse outcomes in patients with suspected infection.
Yesil, Olcay; Pekdemir, Murat; Özturan, Ibrahim Ulas; Dogan, Nurettin Özgür; Yaka, Elif; Yilmaz, Serkan; Karadas, Adnan; Pinar, Seda Güney.
Afiliación
  • Yesil O; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey.
  • Pekdemir M; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey.
  • Özturan IU; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey. ozturan.iu@gmail.com.
  • Dogan NÖ; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey.
  • Yaka E; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey.
  • Yilmaz S; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey.
  • Karadas A; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey.
  • Pinar SG; Faculty of Medicine, Dept. of Emergency Medicine, Kocaeli University, Kabaoglu, Baki Komsuoglu bulvari No:515, Umuttepe, 41001, Izmit, Kocaeli, Turkey.
Med Klin Intensivmed Notfmed ; 117(8): 623-629, 2022 Nov.
Article en En | MEDLINE | ID: mdl-34586431
BACKGROUND: The use of the quick sequential organ failure assessment score (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria to identify patients at high risk for adverse outcomes in the emergency department (ED) remains controversial due to their low predictive performance and lack of supporting evidence. This study aimed to determine the predictive performance of qSOFA, SIRS, and the qSOFA + SIRS combinations for adverse outcomes. METHODS: All adult patients admitted to the ED with suspected infection were prospectively included. qSOFA scores ≥ 2, SIRS score ≥ 2 were defined as risk-positive for adverse outcome. Furthermore, combination­1, which was defined as either qSOFA or SIRS positivity, and combination­2, which was defined as both qSOFA and SIRS positivity, were also considered as risk-positive for adverse outcome. The predictive performance of qSOFA, SIRS, combination­1, and combination­2 for a composite adverse outcome within 30 days, including mortality, intensive care unit (ICU) admission, and non-ICU hospitalization, were determined. RESULTS: A total of 350 patients were included in the analysis. The composite outcome occurred in 211 (60.3%) patients within 30 days: mortality in 84 (24%), ICU admission in 78 (22.3%), and non-ICU hospitalization in 154 (44%). The sensitivity and specificity, respectively, were determined in predicting composite outcome as 0.34 and 0.93 for qSOFA, 0.81 and 0.31 for SIRS, 0.84 and 0.28 for combination­1, and 0.31 and 0.96 for combination­2. CONCLUSION: The study results suggest that qSOFA and combination­2 could be a useful tool for confirming patients at high risk for adverse outcomes. Although SIRS and combination­1 could be helpful for excluding high-risk patients, the requirement of white blood cell counts limits their utilization for screening.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sepsis / Puntuaciones en la Disfunción de Órganos Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Med Klin Intensivmed Notfmed Año: 2022 Tipo del documento: Article País de afiliación: Turquía

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sepsis / Puntuaciones en la Disfunción de Órganos Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Med Klin Intensivmed Notfmed Año: 2022 Tipo del documento: Article País de afiliación: Turquía
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