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Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.
Villiger, Lukas; Schmidheini, Lukas; Mathis, Nicolas; Rothgangl, Tanja; Marquart, Kim; Schwank, Gerald.
Afiliación
  • Villiger L; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.
  • Schmidheini L; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.
  • Mathis N; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.
  • Rothgangl T; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.
  • Marquart K; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.
  • Schwank G; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.
Mol Ther Nucleic Acids ; 26: 502-510, 2021 Dec 03.
Article en En | MEDLINE | ID: mdl-34631280

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Año: 2021 Tipo del documento: Article País de afiliación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Año: 2021 Tipo del documento: Article País de afiliación: Suiza
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