Transarterial embolization with hepatectomy for ruptured hepatocellular carcinoma: a meta-analysis.
Minim Invasive Ther Allied Technol
; 31(5): 676-683, 2022 Jun.
Article
en En
| MEDLINE
| ID: mdl-34634985
ABSTRACT
PURPOSE:
To compare the clinical effectiveness between transarterial embolization (TAE) with staged hepatectomy (SH) and emergency hepatectomy (EH) for ruptured hepatocellular carcinoma (HCC). MATERIAL ANDMETHODS:
Pubmed, Embase, and Cochrane Library databases were screened for eligible publications from the inception of the databases till February 2021.RESULTS:
This meta-analysis included seven studies comprising 162 patients who underwent TAE with SH and 266 patients who underwent EH. The pooled intraoperative blood loss was less in the TAE with SH cohort, as compared to the EH cohort without significant difference (p = .20). The pooled blood transfer rate (p<.00001), blood transfer volume (p = .002), and 30-day patient death (p = .04) were all markedly reduced in the TAE with SH cohort versus the EH cohort. No significant differences in surgery duration (p = .27), hospital stay period (p = .81), complication rate (p = 0.92), disease-free survival (DFS) (p = .79), and overall survival (OS) (p = 0.28) were found between the two groups.CONCLUSIONS:
Compared with EH for ruptured HCC, TAE with SH could effectively decrease intraoperative blood loss and 30-day mortality. However, the long-term DFS and OS might not be beneficial to preoperative TAE.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
6_digestive_diseases
/
6_liver_cancer
Asunto principal:
Carcinoma Hepatocelular
/
Embolización Terapéutica
/
Neoplasias Hepáticas
Tipo de estudio:
Observational_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Minim Invasive Ther Allied Technol
Asunto de la revista:
TERAPEUTICA
Año:
2022
Tipo del documento:
Article
País de afiliación:
China