Localization of the gene for X-linked spinal muscular atrophy.
Neurology
; 36(12): 1595-8, 1986 Dec.
Article
en En
| MEDLINE
| ID: mdl-3466055
ABSTRACT
We used probes for DNA polymorphisms on the X chromosome to study genetic linkage in seven families with X-linked adult-onset spinal muscular atrophy. We found significant linkage to the marker DXYS1 on the proximal X chromosome long arm and loose linkage or nonlinkage to markers elsewhere. Our analysis localizes the gene defect for this form of anterior horn cell disease.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cromosoma X
/
Marcadores Genéticos
/
Ligamiento Genético
/
Distrofias Musculares
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
/
Newborn
Idioma:
En
Revista:
Neurology
Año:
1986
Tipo del documento:
Article