A Case of In Situ Phage Therapy against <i>Staphylococcus aureus</i> in a Bone Allograft Polymicrobial Biofilm Infection: Outcomes and Phage-Antibiotic Interactions.

Van Nieuwenhuyse, Brieuc; Galant, Christine; Brichard, Bénédicte; Docquier, Pierre-Louis; Djebara, Sarah; Pirnay, Jean-Paul; Van der Linden, Dimitri; Merabishvili, Maya; Chatzis, Olga

A Case of In Situ Phage Therapy against Staphylococcus aureus in a Bone Allograft Polymicrobial Biofilm Infection: Outcomes and Phage-Antibiotic Interactions.

Van Nieuwenhuyse, Brieuc; Galant, Christine; Brichard, Bénédicte; Docquier, Pierre-Louis; Djebara, Sarah; Pirnay, Jean-Paul; Van der Linden, Dimitri; Merabishvili, Maya; Chatzis, Olga.

Afiliación

Van Nieuwenhuyse B; Pediatric Department, Institute of Experimental and Clinical Research (IREC/PEDI), Université Catholique de Louvain-UCLouvain, B-1200 Brussels, Belgium.
Galant C; Department of Pathology, Institute of Experimental and Clinical Research, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain-UCLouvain, B-1200 Brussels, Belgium.
Brichard B; Department of Pediatric Haematology, Department of Pediatrics, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain-UCLouvain, B-1200 Brussels, Belgium.
Docquier PL; Department of Orthopedic Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain-UCLouvain, B-1200 Brussels, Belgium.
Djebara S; Center for Infectious Diseases ID4C, Queen Astrid Military Hospital, B-1120 Brussels, Belgium.
Pirnay JP; Laboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, B-1120 Brussels, Belgium.
Van der Linden D; Pediatric Infectious Diseases, General Pediatrics Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain-UCLouvain, B-1200 Brussels, Belgium.
Merabishvili M; Laboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, B-1120 Brussels, Belgium.
Chatzis O; Pediatric Infectious Diseases, General Pediatrics Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain-UCLouvain, B-1200 Brussels, Belgium.

Viruses ; 13(10)2021 09 22.

Article en En | MEDLINE | ID: mdl-34696328

Asunto(s)

Aloinjertos/microbiología; Antibacterianos/farmacología; Huesos/microbiología; Coinfección/terapia; Terapia de Fagos/métodos; Infecciones Estafilocócicas/terapia; Fagos de Staphylococcus/fisiología; Staphylococcus aureus/efectos de los fármacos; Aloinjertos/efectos de los fármacos; Biopelículas; Huesos/efectos de los fármacos; Huesos/patología; Niño; Interacciones Farmacológicas; Femenino; Humanos; Sarcoma de Ewing/tratamiento farmacológico; Infecciones Estafilocócicas/diagnóstico

Palabras clave

Staphylococcus aureus; antibiotic-bacteriophage combination; bacteriophage; chronic osteitis; phage therapy; phage-antibiotic interactions; phage-antibiotic synergy; polymicrobial biofilm

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Staphylococcus aureus / Huesos / Fagos de Staphylococcus / Coinfección / Aloinjertos / Terapia de Fagos / Antibacterianos Tipo de estudio: Diagnostic_studies Límite: Child / Female / Humans Idioma: En Revista: Viruses Año: 2021 Tipo del documento: Article País de afiliación: Bélgica

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