Photon beam modeling variations predict errors in IMRT dosimetry audits.
Radiother Oncol
; 166: 8-14, 2022 01.
Article
en En
| MEDLINE
| ID: mdl-34748857
ABSTRACT
BACKGROUND & PURPOSE:
To evaluate treatment planning system (TPS) beam modeling parameters as contributing factors to IMRT audit performance. MATERIALS &METHODS:
We retrospectively analyzed IROC Houston phantom audit performance and concurrent beam modeling survey responses from 337 irradiations performed between August 2017 and November 2019. Irradiation results were grouped based on the reporting of typical or atypical beam modeling parameter survey responses (<10th or >90th percentile values), and compared for passing versus failing (>7% error) or "poor" (>5% error) irradiation status. Additionally, we assessed the impact on the planned dose distribution from variations in modeling parameter value. Finally, we estimated the overall impact of beam modeling parameter variance on dose calculations, based on reported community variations.RESULTS:
Use of atypical modeling parameters were more frequently seen with failing phantom audit results (p = 0.01). Most pronounced was for Eclipse AAA users, where phantom irradiations with atypical values of dosimetric leaf gap (DLG) showed a greater incidence of both poor-performing (p = 0.048) and failing phantom audits (p = 0.014); and in general, DLG value was correlated with dose calculation accuracy (r = 0.397, p < 0.001). Manipulating TPS parameters induced systematic changes in planned dose distributions which were consistent with prior observations of how failures manifest. Dose change estimations based on these dose calculations agreed well with true dosimetric errors identified.CONCLUSION:
Atypical TPS beam modeling parameters are associated with failing phantom audits. This is identified as an important factor contributing to the observed failing phantom results, and highlights the need for accurate beam modeling.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Radioterapia de Intensidad Modulada
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Radiother Oncol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos