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Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function.
Barbuti, Peter A; Ohnmacht, Jochen; Santos, Bruno F R; Antony, Paul M; Massart, François; Cruciani, Gérald; Dording, Claire M; Pavelka, Lukas; Casadei, Nicolas; Kwon, Yong-Jun; Krüger, Rejko.
Afiliación
  • Barbuti PA; Translational Neuroscience, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4362, Esch-sur-Alzette, Luxembourg. pab2184@cumc.columbia.edu.
  • Ohnmacht J; Transversal Translational Medicine, Luxembourg Institute of Health, 1445, Strassen, Luxembourg. pab2184@cumc.columbia.edu.
  • Santos BFR; Department of Neurology, Columbia University Irving Medical Center, New York, NY, 10032, USA. pab2184@cumc.columbia.edu.
  • Antony PM; Translational Neuroscience, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4362, Esch-sur-Alzette, Luxembourg.
  • Massart F; Department of Life Science and Medicine, University of Luxembourg, 4362, Esch-sur-Alzette, Luxembourg.
  • Cruciani G; Translational Neuroscience, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4362, Esch-sur-Alzette, Luxembourg.
  • Dording CM; Transversal Translational Medicine, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
  • Pavelka L; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre for Systems Biomedicine, University of Luxembourg & Luxembourg Institute of Health, 6 avenue du Swing, 4367, Belvaux, Luxembourg.
  • Casadei N; Translational Neuroscience, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4362, Esch-sur-Alzette, Luxembourg.
  • Kwon YJ; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre for Systems Biomedicine, University of Luxembourg & Luxembourg Institute of Health, 6 avenue du Swing, 4367, Belvaux, Luxembourg.
  • Krüger R; Translational Neuroscience, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4362, Esch-sur-Alzette, Luxembourg.
Sci Rep ; 11(1): 21946, 2021 11 09.
Article en En | MEDLINE | ID: mdl-34754035

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Alfa-Sinucleína / Neuronas Dopaminérgicas / Mutación Límite: Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Luxemburgo

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Alfa-Sinucleína / Neuronas Dopaminérgicas / Mutación Límite: Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Luxemburgo
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