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Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear Magnetic Resonance Spectroscopy.
Lu, Xingyu; Li, Mingyue; Arce, Freddy A; Ling, Jing; Setiawan, Nico; Wang, Yaqiang; Shi, Xiaohuo; Campbell, Heather R; Nethercott, Matthew J; Xu, Wei; Munson, Eric J; Marsac, Patrick J; Su, Yongchao.
Afiliación
  • Lu X; Analytical Research and Development, Merck & Co., Rahway, New Jersey 07065, United States.
  • Li M; Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province, School of Science, Westlake University, Hangzhou, Zhejiang 310024, China.
  • Arce FA; Analytical Research and Development, Merck & Co., Rahway, New Jersey 07065, United States.
  • Ling J; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
  • Setiawan N; Pharmaceutical Sciences, Merck & Co., South San Francisco, California 94080, United States.
  • Wang Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
  • Shi X; Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California 90095 United States.
  • Campbell HR; Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province, School of Science, Westlake University, Hangzhou, Zhejiang 310024, China.
  • Nethercott MJ; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
  • Xu W; Kansas Analytical Services, LLC, Loveland, Colorado 80537, United States.
  • Munson EJ; Analytical Research and Development, Merck & Co., Rahway, New Jersey 07065, United States.
  • Marsac PJ; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.
  • Su Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
Mol Pharm ; 18(12): 4310-4321, 2021 12 06.
Article en En | MEDLINE | ID: mdl-34761934
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisorbatos / Espectroscopía de Resonancia Magnética / Estradiol Tipo de estudio: Prognostic_studies Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisorbatos / Espectroscopía de Resonancia Magnética / Estradiol Tipo de estudio: Prognostic_studies Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos