[Plasma cytomegalovirus viremia prevalence among HIV-infected individuals: a Meta-analysis].
Zhonghua Liu Xing Bing Xue Za Zhi
; 42(4): 723-727, 2021 Apr 10.
Article
en Zh
| MEDLINE
| ID: mdl-34814458
ABSTRACT
Objective:
To understand the prevalence and correlates of plasma cytomegalovirus (CMV) viremia among HIV-infected individuals by Meta-analysis.Methods:
A systematic literature retrieval was conducted by PubMed, CNKI, Wanfang, and VIP databases for the information about the prevalence of plasma CMV viremia among HIV-infected individuals published from 2011 to 2020. Meta-analysis was used to calculate the pooled prevalence after literature screening and data extraction.Results:
Fifteen studies were included, and the total sample size was 5 076. The random effect model showed that the pooled prevalence of CMV viremia among HIV-infected individuals was 26.2% (95%CI 16.8%-35.6%, I2=99%); Subgroup analysis and Meta-regression showed that the sources of heterogeneity among different studies were the proportion of individuals aged >30 years in sample, the proportion of homosexual transmission in the sample, the proportion of individuals whose HIV viral load > 104 copies/ml, the proportion of individuals whose CD4+T lymphocyte counts <200 cells/µl.Conclusion:
Among HIV-infected individuals, the prevalence of CMV viremia was high and might be associated with age, HIV transmission mode, the status of HIV/AIDS.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Infecciones por Citomegalovirus
Tipo de estudio:
Prevalence_studies
/
Risk_factors_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
Zh
Revista:
Zhonghua Liu Xing Bing Xue Za Zhi
Año:
2021
Tipo del documento:
Article
País de afiliación:
China