Experimental and simulation studies reveal mechanism of action of human defensin derivatives.

Rani, Lata; Arora, Ankita; Majhi, Sasmita; Mishra, Abhijit; Mallajosyula, Sairam S

Rani, Lata; Arora, Ankita; Majhi, Sasmita; Mishra, Abhijit; Mallajosyula, Sairam S.

Afiliación

Rani L; Department of Chemistry, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India.
Arora A; Department of Materials Science and Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India.
Majhi S; Department of Materials Science and Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India.
Mishra A; Department of Materials Science and Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India. Electronic address: amishra@iitgn.ac.in.
Mallajosyula SS; Department of Chemistry, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India. Electronic address: msairam@iitgn.ac.in.

Biochim Biophys Acta Biomembr ; 1864(2): 183824, 2022 02 01.

Article en En | MEDLINE | ID: mdl-34838874

Asunto(s)

Antibacterianos/farmacología; Péptidos Catiónicos Antimicrobianos/farmacología; Bacterias/efectos de los fármacos; Fibroblastos/efectos de los fármacos; Membrana Dobles de Lípidos/metabolismo; Simulación de Dinámica Molecular; beta-Defensinas/farmacología; Animales; Humanos; Ratones; Ratones Endogámicos C3H

Palabras clave

Antibacterial assay; Antimicrobial peptides; Cell-penetrating peptides; Molecular dynamics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Péptidos Catiónicos Antimicrobianos / Beta-Defensinas / Simulación de Dinámica Molecular / Fibroblastos / Membrana Dobles de Lípidos / Antibacterianos Límite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Biomembr Año: 2022 Tipo del documento: Article País de afiliación: India

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