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Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.
van de Veerdonk, Frank L; Renga, Giorgia; Pariano, Marilena; Bellet, Marina M; Servillo, Giuseppe; Fallarino, Francesca; De Luca, Antonella; Iannitti, Rossana G; Piobbico, Danilo; Gargaro, Marco; Manni, Giorgia; D'Onofrio, Fiorella; Stincardini, Claudia; Sforna, Luigi; Borghi, Monica; Castelli, Marilena; Pieroni, Stefania; Oikonomou, Vasileios; Villella, Valeria R; Puccetti, Matteo; Giovagnoli, Stefano; Galarini, Roberta; Barola, Carolina; Maiuri, Luigi; Della Fazia, Maria Agnese; Cellini, Barbara; Talesa, Vincenzo Nicola; Dinarello, Charles A; Costantini, Claudio; Romani, Luigina.
Afiliación
  • van de Veerdonk FL; Department of Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
  • Renga G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Pariano M; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Bellet MM; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Servillo G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Fallarino F; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • De Luca A; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Iannitti RG; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Piobbico D; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Gargaro M; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Manni G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • D'Onofrio F; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Stincardini C; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Sforna L; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Borghi M; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Castelli M; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Pieroni S; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Oikonomou V; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Villella VR; European Institute for Research in Cystic Fibrosis, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
  • Puccetti M; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.
  • Giovagnoli S; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.
  • Galarini R; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati," Perugia, Italy.
  • Barola C; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati," Perugia, Italy.
  • Maiuri L; European Institute for Research in Cystic Fibrosis, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
  • Della Fazia MA; Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
  • Cellini B; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Talesa VN; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Dinarello CA; Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Costantini C; Department of Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
  • Romani L; Department of Medicine, University of Colorado, Aurora, Colorado, USA.
J Clin Invest ; 132(2)2022 01 18.
Article en En | MEDLINE | ID: mdl-34847078
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Estrés Oxidativo / Proteína Antagonista del Receptor de Interleucina 1 / Proteostasis / Mitocondrias Límite: Animals Idioma: En Revista: J Clin Invest Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Estrés Oxidativo / Proteína Antagonista del Receptor de Interleucina 1 / Proteostasis / Mitocondrias Límite: Animals Idioma: En Revista: J Clin Invest Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos