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Integrated RNAi screening identifies the NEDDylation pathway as a synergistic partner of azacytidine in acute myeloid leukemia.
Klosner, Justine; Agelopoulos, Konstantin; Rohde, Christian; Göllner, Stefanie; Schliemann, Christoph; Berdel, Wolfgang E; Müller-Tidow, Carsten.
Afiliación
  • Klosner J; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, Münster, Germany. justine.klosner@ukmuenster.de.
  • Agelopoulos K; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
  • Rohde C; Department of Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
  • Göllner S; Department of Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
  • Schliemann C; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, Münster, Germany.
  • Berdel WE; Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, Münster, Germany.
  • Müller-Tidow C; Department of Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
Sci Rep ; 11(1): 23280, 2021 12 02.
Article en En | MEDLINE | ID: mdl-34857808
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azacitidina / Leucemia Mieloide Aguda / Transducción de Señal / Interferencia de ARN / Proteína NEDD8 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azacitidina / Leucemia Mieloide Aguda / Transducción de Señal / Interferencia de ARN / Proteína NEDD8 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Alemania