Tricking enzymes in living cells: a mechanism-based strategy for design of DNA topoisomerase biosensors.

Ba, Sai; Gao, Guangpeng; Li, Tianhu; Zhang, Hao

Ba, Sai; Gao, Guangpeng; Li, Tianhu; Zhang, Hao.

Afiliación

Ba S; School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, 710072, China.
Gao G; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore.
Li T; School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, 710072, China.
Zhang H; School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, 710072, China. tianhuli@nwpu.edu.cn.

J Nanobiotechnology ; 19(1): 407, 2021 Dec 07.

Article en En | MEDLINE | ID: mdl-34876137

Asunto(s)

Técnicas Biosensibles/métodos; ADN-Topoisomerasas; Sondas Moleculares; Neoplasias; Sistema Libre de Células; Células Cultivadas; ADN/química; ADN/metabolismo; ADN-Topoisomerasas/análisis; ADN-Topoisomerasas/química; ADN-Topoisomerasas/genética; ADN-Topoisomerasas/metabolismo; Humanos; Sondas Moleculares/química; Sondas Moleculares/metabolismo; Nanotecnología; Neoplasias/diagnóstico; Neoplasias/metabolismo

Palabras clave

Cancer diagnosis; DNA nanotechnology; DNA topoisomerases; Diagnostic probes; Enzyme mechanisms

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Sondas Moleculares / ADN-Topoisomerasas / Neoplasias Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Nanobiotechnology Año: 2021 Tipo del documento: Article País de afiliación: China

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