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Nosocomial infection with rotavirus vaccine strain in paediatric patients with immunodeficiency.
Miura, H; Taniguchi, K; Narita, K; Kawamura, Y; Kozawa, K; Muramatsu, H; Takahashi, Y; Ihira, M; Yoshikawa, T.
Afiliación
  • Miura H; Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; Department of Dermatology, School of Medicine, University of California Davis (UC Davis), Sacramento, CA, USA. Electronic address: hiroki-m@fujita-hu.ac.jp.
  • Taniguchi K; Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
  • Narita K; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Kawamura Y; Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
  • Kozawa K; Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
  • Muramatsu H; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Takahashi Y; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Ihira M; Faculty of Clinical Engineering, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan.
  • Yoshikawa T; Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
J Hosp Infect ; 121: 9-13, 2022 Mar.
Article en En | MEDLINE | ID: mdl-34915052
In infants with immunodeficiency, rotavirus (RV) vaccines can be continuously excreted in stool. We analysed nosocomial infection with RV vaccine strain in immunodeficient paediatric patients. RV1 RNAs were detected in stool and serum samples from case A, who was vaccinated with RV1, and case B, who was not. PAGE analysis of serial stool samples of case A revealed several rearrangements of the RV genome. In case B, the only band pattern detected was the same as a rearrangement detected in case A at the same time. In summary, RV vaccination of infants with immunodeficiency poses a risk of nosocomial infections.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 2_ODS3 / 3_ND / 4_TD Problema de salud: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_diarrhea / 4_diarrhoeal_infections Asunto principal: Infecciones por Rotavirus / Infección Hospitalaria / Rotavirus / Vacunas contra Rotavirus Límite: Child / Humans / Infant Idioma: En Revista: J Hosp Infect Año: 2022 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 2_ODS3 / 3_ND / 4_TD Problema de salud: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_diarrhea / 4_diarrhoeal_infections Asunto principal: Infecciones por Rotavirus / Infección Hospitalaria / Rotavirus / Vacunas contra Rotavirus Límite: Child / Humans / Infant Idioma: En Revista: J Hosp Infect Año: 2022 Tipo del documento: Article