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Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy.
Ou, Weijun; Yang, Joshua; Simanauskaite, Juste; Choi, Matthew; Castellanos, Demi M; Chang, Rudy; Sun, Jiahong; Jagadeesan, Nataraj; Parfitt, Karen D; Cribbs, David H; Sumbria, Rachita K.
Afiliación
  • Ou W; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
  • Yang J; Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, Claremont, CA, 91711, USA.
  • Simanauskaite J; Department of Neuroscience, Pomona College, Claremont, CA, 91711, USA.
  • Choi M; Keck Science Department, Claremont McKenna College, Claremont, CA, 91711, USA.
  • Castellanos DM; Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, Claremont, CA, 91711, USA.
  • Chang R; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
  • Sun J; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
  • Jagadeesan N; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
  • Parfitt KD; Department of Neuroscience, Pomona College, Claremont, CA, 91711, USA.
  • Cribbs DH; MIND Institute, University of California, Irvine, CA, 92697, USA.
  • Sumbria RK; Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, CA, 92618, USA. sumbria@chapman.edu.
J Neuroinflammation ; 18(1): 312, 2021 Dec 31.
Article en En | MEDLINE | ID: mdl-34972522
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Factor de Necrosis Tumoral alfa / Proteínas tau / Tauopatías / Gliosis / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Factor de Necrosis Tumoral alfa / Proteínas tau / Tauopatías / Gliosis / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos