Dataset for dynamics and conformational changes in human NEIL2 protein analyzed by integrative structural biology approach.

Zhdanova, Polina V; Ishchenko, Alexander A; Chernonosov, Alexander A; Zharkov, Dmitry O; Koval, Vladimir V

Zhdanova, Polina V; Ishchenko, Alexander A; Chernonosov, Alexander A; Zharkov, Dmitry O; Koval, Vladimir V.

Afiliación

Zhdanova PV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibisk, Russia.
Ishchenko AA; Novosibirsk State University, Novosibisk, Russia.
Chernonosov AA; Groupe «Réparation de l'ADN¼, Equipe Labellisée par la Ligue Nationale contre le Cancer, CNRS UMR 8200, Univ. Paris-Sud, Université Paris-Saclay, Villejuif F-94805, France.
Zharkov DO; Gustave Roussy, Université Paris-Saclay, Villejuif F-94805, France.
Koval VV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibisk, Russia.

Data Brief ; 40: 107760, 2022 Feb.

Article en En | MEDLINE | ID: mdl-35005149

Palabras clave

Base excision repair; CD, circular dichroism; DNA damage; DNA glycosylases; DNA repair; DTT, (2S,3S)-1,4-Bis(sulfanyl)butane-2,3-diol; ESI, electrospray ionization; HDX-MS; HDX-MS, hydrogen-deuterium exchange mass spectrometry; HEPES, 2-[4-(2-Hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid; IPTG, Propan-2-yl 1-thio-ß-D-galactopyranoside; LB, Lysogeny broth; LC-MS, liquid chromatographymass spectrometry; MD, molecular dynamics; MDTRA, Molecular Dynamics Trajectory Reader & Analyzer; Molecular dynamics; NEIL2; PDB, Protein Data Bank; RMSD, root-mean-square deviation; SDS-PAGE, sodium dodecyl sulphatepolyacrylamide gel electrophoresis; Structural dynamics; TCEP, 3,3',3''-Phosphanetriyltripropanoic acid; hNEIL2, human endonuclease VIII-like 2 protein

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Data Brief Año: 2022 Tipo del documento: Article País de afiliación: Rusia