Dataset for dynamics and conformational changes in human NEIL2 protein analyzed by integrative structural biology approach.
Data Brief
; 40: 107760, 2022 Feb.
Article
en En
| MEDLINE
| ID: mdl-35005149
Base excision repair; CD, circular dichroism; DNA damage; DNA glycosylases; DNA repair; DTT, (2S,3S)-1,4-Bis(sulfanyl)butane-2,3-diol; ESI, electrospray ionization; HDX-MS; HDX-MS, hydrogen-deuterium exchange mass spectrometry; HEPES, 2-[4-(2-Hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid; IPTG, Propan-2-yl 1-thio-ß-D-galactopyranoside; LB, Lysogeny broth; LC-MS, liquid chromatographymass spectrometry; MD, molecular dynamics; MDTRA, Molecular Dynamics Trajectory Reader & Analyzer; Molecular dynamics; NEIL2; PDB, Protein Data Bank; RMSD, root-mean-square deviation; SDS-PAGE, sodium dodecyl sulphatepolyacrylamide gel electrophoresis; Structural dynamics; TCEP, 3,3',3''-Phosphanetriyltripropanoic acid; hNEIL2, human endonuclease VIII-like 2 protein
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01-internacional
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MEDLINE
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En
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Data Brief
Año:
2022
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Article
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Rusia