Generation of Lasso Peptide-Based ClpP Binders.

Malik, Imran T; Hegemann, Julian D; Brötz-Oesterhelt, Heike

Malik, Imran T; Hegemann, Julian D; Brötz-Oesterhelt, Heike.

Afiliación

Malik IT; Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, 72076 Tübingen, Germany.
Hegemann JD; Helmholtz Centre for Infection Research (HZI), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarland University Campus, 66123 Saarbrücken, Germany.
Brötz-Oesterhelt H; Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, 72076 Tübingen, Germany.

Int J Mol Sci ; 23(1)2021 Dec 31.

Article en En | MEDLINE | ID: mdl-35008890

Asunto(s)

Bacillus subtilis; Endopeptidasa Clp; Staphylococcus aureus; Bacillus subtilis/genética; Bacillus subtilis/metabolismo; Endopeptidasa Clp/genética; Endopeptidasa Clp/metabolismo; Proteolisis; Staphylococcus aureus/genética; Staphylococcus aureus/metabolismo

Palabras clave

ADEP; Clp ATPase; Clp protease; acyldepsipeptide; bioengineering; epitope grafting; lasso peptide; mutagenesis; natural product; proteolysis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus / Bacillus subtilis / Endopeptidasa Clp Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Alemania

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