External Validation of the Patient-Reported Villalta Scale for the Diagnosis of Postthrombotic Syndrome.
Thromb Haemost
; 122(8): 1379-1383, 2022 Aug.
Article
en En
| MEDLINE
| ID: mdl-35021257
ABSTRACT
INTRODUCTION:
The Villalta scale is the endorsed tool to diagnose and grade the severity of postthrombotic syndrome (PTS); however, assessing presence and severity of PTS is time-consuming and relies on both the clinician and patient's assessments. The patient-reported Villalta scale version 2 (PRV2) is a visually assisted form that enables patients to self-assess presence and severity of PTS. Herein, we report on external validation of this tool.METHODS:
We assessed the agreement and kappa values of PRV2 to diagnose and assess severity of PTS compared with the original Villalta score in a cohort of 181 patients (196 limbs) who participated in the SAVER pilot randomized control trial. Presence of PTS was defined as PRV2 ≥5 or a Villalta score ≥5.RESULTS:
PTS prevalence was 42% using PRV2 and 33% using the Villalta scale. The corresponding kappa and percentage agreement were 0.60 (95% confidence interval [CI] 0.49-0.71) and 81% (95% CI 76-87), respectively. Kappa values and percentage agreements between PRV2 and Villalta scale increased with increasing severity of PTS. The sensitivity of PRV2 to detect PTS of any severity was 84% (95% CI 73-92) with a specificity of 79% (95% CI 71-86).CONCLUSION:
We conclude that the PRV2 is an acceptable tool for diagnosing and grading the severity of PTS.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome Posflebítico
/
Trombosis de la Vena
/
Síndrome Postrombótico
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Prevalence_studies
/
Risk_factors_studies
Aspecto:
Patient_preference
Límite:
Humans
Idioma:
En
Revista:
Thromb Haemost
Año:
2022
Tipo del documento:
Article
País de afiliación:
Canadá