Evaluation of the effects of total intravenous anesthesia and inhalation anesthesia on postoperative cognitive recovery.
Anaesthesiologie
; 72(Suppl 1): 19-24, 2023 12.
Article
en En
| MEDLINE
| ID: mdl-35024878
ABSTRACT
OBJECTIVE:
To compare the effects of total intravenous anesthesia (TIVA) and inhalation anesthesia (IA) used in lumbar disc herniectomy on postoperative cognitive recovery based on the mini-mental state examination (MMSE) score and neuron-specific enolase (NSE) levels. MATERIAL ANDMETHODS:
The study sample consisted of 80 patients aged 18-65 years who were scheduled for elective lumbar disc herniectomy. The patients were divided into two groups according to the anesthesia technique applied, such as TIVA or IA. The patients in the TIVA group were administered remifentanil and propofol and those in the IA group were administered sevoflurane for maintenance. The MMSE was applied to the patients before the operation and 1h and 24â¯h postoperatively. Venous blood samples were obtained for the measurement of NSE before the operation and on the 24â¯h postoperatively.RESULTS:
The mean preoperative MMSE scores were similar in the two groups. In the TIVA group, the preoperative and postoperative MMSE scores at 1â¯h were similar but were higher at 24â¯h postoperatively compared to the previous two scores (pâ¯= 0.001 and pâ¯< 0.001, respectively). In the IA group, the preoperative and postoperative 24â¯h MMSE scores were similar but lower at 1h postoperatively than the other two scores (pâ¯= 0.006 and pâ¯< 0.001, respectively). In the TIVA group, there was a significant decrease in the postoperative serum NSE levels than the preoperative values (pâ¯= 0.038).CONCLUSION:
The use of IA may result in higher cognitive dysfunction 1h after the operation compared to TIVA. The effects of both methods on cognitive functions were similar at 24â¯h postoperatively.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Anestésicos Intravenosos
/
Anestesia Intravenosa
Límite:
Humans
Idioma:
En
Revista:
Anaesthesiologie
Año:
2023
Tipo del documento:
Article
País de afiliación:
Turquía