[Clinical approach for periocular lymphoma]. / Klinisches Vorgehen bei periokulären Lymphomen.

BACKGROUND: Lymphomas occur very frequently in the periocular region, predominantly in adulthood. This malignant tumor shows a heterogeneous clinical pattern. AIM: The aim of this article is to provide an overview of the symptoms, diagnostic procedures and treatment options for lymphomas of the periocular region. SYMPTOMS: The symptoms of periocular lymphomas are mostly nonspecific. The growth is usually painless and slowly progressive. A salmon-colored swelling is typical for conjunctival lymphoma. DIAGNOSTICS: The basis of a precise diagnostic process is a detailed anamnesis. Contrast-enhanced magnetic resonance imaging (MRI) is considered the gold standard for imaging of lymphoproliferative lesions. A histopathological examination should be carried out to confirm the exact diagnosis. Subsequently, staging should be performed as periocular lymphomas can be the manifestation of a systemic involvement. TREATMENT: The treatment procedure should be coordinated by an interdisciplinary tumor board. The treatment of periocular lymphomas can include percutaneous stereotactic irradiation as well as chemotherapeutic or new immunotherapeutic strategies.