Sex- and strain-specific effects of mitochondrial uncoupling on age-related metabolic diseases in high-fat diet-fed mice.

Goedeke, Leigh; Murt, Kelsey N; Di Francesco, Andrea; Camporez, João Paulo; Nasiri, Ali R; Wang, Yongliang; Zhang, Xian-Man; Cline, Gary W; de Cabo, Rafael; Shulman, Gerald I

Goedeke, Leigh; Murt, Kelsey N; Di Francesco, Andrea; Camporez, João Paulo; Nasiri, Ali R; Wang, Yongliang; Zhang, Xian-Man; Cline, Gary W; de Cabo, Rafael; Shulman, Gerald I.

Afiliación

Goedeke L; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Murt KN; Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Di Francesco A; Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Camporez JP; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Nasiri AR; Department of Physiology, Ribeirao Preto School of Medicine, University of Sao Paulo, São Paulo, Brazil.
Wang Y; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Zhang XM; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Cline GW; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
de Cabo R; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Shulman GI; Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland, USA.

Aging Cell ; 21(2): e13539, 2022 02.

Article en En | MEDLINE | ID: mdl-35088525

Asunto(s)

Carcinoma Hepatocelular; Resistencia a la Insulina; Neoplasias Hepáticas; Animales; Carcinoma Hepatocelular/metabolismo; Dieta Alta en Grasa/efectos adversos; Femenino; Hígado/metabolismo; Neoplasias Hepáticas/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Mitocondrias/metabolismo

Palabras clave

2,4-dinitrophenol; anti-aging; hepatic steatosis; insulin sensitivity; longevity; mitochondrial uncoupling

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Carcinoma Hepatocelular / Neoplasias Hepáticas Límite: Animals Idioma: En Revista: Aging Cell Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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