Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19.

Nln, Ilona; Fernandez-Ruiz, Ruth; Muskardin, Theresa L Wampler; Paredes, Jacqueline L; Blazer, Ashira D; Tuminello, Stephanie; Attur, Mukundan; Iturrate, Eduardo; Petrilli, Christopher M; Abramson, Steven B; Chakravarti, Aravinda; Niewold, Timothy B

Nln, Ilona; Fernandez-Ruiz, Ruth; Muskardin, Theresa L Wampler; Paredes, Jacqueline L; Blazer, Ashira D; Tuminello, Stephanie; Attur, Mukundan; Iturrate, Eduardo; Petrilli, Christopher M; Abramson, Steven B; Chakravarti, Aravinda; Niewold, Timothy B.

Afiliación

Nln I; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, New York.
Fernandez-Ruiz R; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, New York.
Muskardin TLW; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, New York.
Paredes JL; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, New York.
Blazer AD; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, New York.
Tuminello S; Center for Human Genetics and Genomics, NYU Grossman School of Medicine, New York, New York.
Attur M; Divison of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, New York, New York.
Iturrate E; Department of Medicine, NYU Grossman School of Medicine, New York, New York.
Petrilli CM; Department of Medicine, NYU Grossman School of Medicine, New York, New York.
Abramson SB; Department of Medicine, NYU Grossman School of Medicine, New York, New York.
Chakravarti A; Center for Human Genetics and Genomics, NYU Grossman School of Medicine, New York, New York.
Niewold TB; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, New York. Electronic address: Timothy.Niewold@nyulangone.org.

Transl Res ; 244: 47-55, 2022 06.

Article en En | MEDLINE | ID: mdl-35114420

Asunto(s)

COVID-19; Lupus Eritematoso Sistémico; Anciano; Alelos; Antivirales; COVID-19/genética; Predisposición Genética a la Enfermedad; Humanos; Factores Reguladores del Interferón/genética; Factores Reguladores del Interferón/metabolismo; Interferón-alfa/genética; Lupus Eritematoso Sistémico/genética; Persona de Mediana Edad; Polimorfismo de Nucleótido Simple

Palabras clave

BMI = body mass index; COVID-19 = coronavirus disease 2019; CRP = C-reactive protein; IFIH1 = interferon-induced with helicase c domain 1; IFN = interferon; IRF = interferon regulatory factor; NYU = New York University; OR = odds ratio; PRKG1 = protein kinase cGMP-dependent 1; SLE = systemic lupus erythematosus; SNP = single nucleotide polymorphism; STAT4 = signal transducer and activator of transcription 4

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Aged / Humans / Middle aged Idioma: En Revista: Transl Res Asunto de la revista: MEDICINA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2022 Tipo del documento: Article

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