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Clinical implications of combination therapy with quizartinib and craniospinal irradiation for refractory acute myeloid leukemia positive for FMS-like tyrosine kinase 3-internal tandem duplication with central nervous system involvement.
Suga, Makiko; Fukushima, Kentaro; Ueda, Tomoaki; Arai, Yasuyuki; Nakagawa, Shunsaku; Minami, Yosuke; Toda, Jun; Hino, Akihisa; Fujita, Jiro; Yokota, Takafumi; Hosen, Naoki.
Afiliación
  • Suga M; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
  • Fukushima K; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
  • Ueda T; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
  • Arai Y; Department of Hematology and Oncology Kyoto University Hospital Kyoto Japan.
  • Nakagawa S; Department of Clinical Pharmacology and Therapeutics Kyoto University Hospital Kyoto Japan.
  • Minami Y; Department of Hematology National Cancer Center Hospital East Kashiwa Japan.
  • Toda J; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
  • Hino A; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
  • Fujita J; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
  • Yokota T; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
  • Hosen N; Department of Hematology and Oncology Osaka University Graduate School of Medicine Suita Japan.
Clin Case Rep ; 10(2): e05384, 2022 Feb.
Article en En | MEDLINE | ID: mdl-35140970
ABSTRACT
FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) mutation-positive acute myeloid leukemia (AML) has a poor prognosis. We report the first case of successful bridge therapy of novel FLT3 inhibitor, quizartinib, to umbilical cord blood stem cell transplantation for FLT3-ITD-positive AML-primary induction failure patients with central nervous system involvement.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Clin Case Rep Año: 2022 Tipo del documento: Article
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Clin Case Rep Año: 2022 Tipo del documento: Article