Establishment of a developmental toxicity assay based on human iPSC reporter to detect FGF signal disruption.

Kanno, Seiya; Okubo, Yusuke; Kageyama, Tatsuto; Yan, Lei; Kitajima, Satoshi; Fukuda, Junji

Kanno, Seiya; Okubo, Yusuke; Kageyama, Tatsuto; Yan, Lei; Kitajima, Satoshi; Fukuda, Junji.

Afiliación

Kanno S; Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya Ward, Yokohama, Kanagawa 240-8501, Japan.
Okubo Y; Division of Cellular & Molecular Toxicology, Center for Biological Safety & Research, National Institute of Health Sciences, 3-25-26 Tono-machi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.
Kageyama T; TechnoPro, Inc., 6-10-1 Roppongi, Minato City, Tokyo 106-6135, Japan.
Yan L; Division of Cellular & Molecular Toxicology, Center for Biological Safety & Research, National Institute of Health Sciences, 3-25-26 Tono-machi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.
Kitajima S; Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya Ward, Yokohama, Kanagawa 240-8501, Japan.
Fukuda J; Kanagawa Institute of Industrial Science and Technology (KISTEC), 3-2-1 Sakado, Takatsu Ward, Kawasaki, Kanagawa 213-0012, Japan.

iScience ; 25(2): 103770, 2022 Feb 18.

Article en En | MEDLINE | ID: mdl-35146387

Palabras clave

Embryology; Pharmacological parameters; Toxicity assessment; Toxicology evaluation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: IScience Año: 2022 Tipo del documento: Article País de afiliación: Japón

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