Recent Developments in Targeting Bromodomain and Extra Terminal Domain Proteins for Cancer Therapeutics.

Cai, Maohua; Dong, Jinyun; Li, Haobin; Qin, Jiang-Jiang

Cai, Maohua; Dong, Jinyun; Li, Haobin; Qin, Jiang-Jiang.

Afiliación

Cai M; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou310022, China.
Dong J; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Li H; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou310022, China.
Qin JJ; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou310022, China.

Curr Med Chem ; 29(25): 4391-4409, 2022.

Article en En | MEDLINE | ID: mdl-35152859

Asunto(s)

Neoplasias; Proteínas Nucleares; Proteínas de Ciclo Celular/metabolismo; Humanos; Neoplasias/tratamiento farmacológico; Neoplasias/metabolismo; Proteínas Nucleares/metabolismo; Dominios Proteicos; Proteolisis; Factores de Transcripción/metabolismo

Palabras clave

BET; BRD4; Cancer; PROTAC; drug design; inhibitor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Curr Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: China

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