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The regulative effect and repercussion of probiotics and prebiotics on osteoporosis: involvement of brain-gut-bone axis.
Zhang, Yuan-Wei; Cao, Mu-Min; Li, Ying-Juan; Dai, Guang-Chun; Lu, Pan-Pan; Zhang, Ming; Bai, Li-Yong; Chen, Xiang-Xu; Zhang, Cheng; Shi, Liu; Rui, Yun-Feng.
Afiliación
  • Zhang YW; Department of Orthopaedics, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Cao MM; Multidisciplinary Team (MDT) for Geriatric Hip Fracture Management, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Li YJ; School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Dai GC; Orthopaedic Trauma Institute (OTI), Southeast University, Nanjing, Jiangsu, P.R. China.
  • Lu PP; Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Zhang M; Department of Orthopaedics, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Bai LY; Multidisciplinary Team (MDT) for Geriatric Hip Fracture Management, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Chen XX; School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Zhang C; Orthopaedic Trauma Institute (OTI), Southeast University, Nanjing, Jiangsu, P.R. China.
  • Shi L; Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
  • Rui YF; Multidisciplinary Team (MDT) for Geriatric Hip Fracture Management, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, P.R. China.
Crit Rev Food Sci Nutr ; 63(25): 7510-7528, 2023.
Article en En | MEDLINE | ID: mdl-35234534
ABSTRACT
Osteoporosis (OP) is a systemic disease characterized by decreased bone mass and degeneration of bone microstructure. In recent years, more and more researches have focused on the close relationship between gut microbiota (GM) and the occurrence and progression of OP, and the regulation of probiotics and prebiotics on bone metabolism has gradually become a research hotspot. Based on the influence of brain-gut-bone axis on bone metabolism, this review expounds the potential mechanisms of probiotics and prebiotics on OP from next perspectives regulation of intestinal metabolites, regulation of intestinal epithelial barrier function, involvement of neuromodulation, involvement of immune regulation and involvement of endocrine regulation, so as to provide a novel and promising idea for the prevention and treatment of OP in the future.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Probióticos Límite: Humans Idioma: En Revista: Crit Rev Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Probióticos Límite: Humans Idioma: En Revista: Crit Rev Food Sci Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2023 Tipo del documento: Article
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