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Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing.
Peterka, Martin; Akrap, Nina; Li, Songyuan; Wimberger, Sandra; Hsieh, Pei-Pei; Degtev, Dmitrii; Bestas, Burcu; Barr, Jack; van de Plassche, Stijn; Mendoza-Garcia, Patricia; Svikovic, Sasa; Sienski, Grzegorz; Firth, Mike; Maresca, Marcello.
Afiliación
  • Peterka M; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden. martin.peterka@astrazeneca.com.
  • Akrap N; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Li S; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Wimberger S; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Hsieh PP; Department of Chemistry & Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
  • Degtev D; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Bestas B; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Barr J; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • van de Plassche S; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Mendoza-Garcia P; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Svikovic S; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Sienski G; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Firth M; Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D Unit, AstraZeneca, Gothenburg, Sweden.
  • Maresca M; Data Sciences and Quantitative Biology, Discovery Sciences, AstraZeneca, Cambridge, UK.
Nat Commun ; 13(1): 1240, 2022 03 24.
Article en En | MEDLINE | ID: mdl-35332138
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Roturas del ADN de Doble Cadena / Reparación del ADN por Unión de Extremidades Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Roturas del ADN de Doble Cadena / Reparación del ADN por Unión de Extremidades Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Suecia