Simultaneous proteasome and autophagy inhibition synergistically enhances cytotoxicity of doxorubicin in breast cancer cells.

Loh, Jian Sheng; Rahim, Nusaibah Abdul; Tor, Yin Sim; Foo, Jhi Biau

Loh, Jian Sheng; Rahim, Nusaibah Abdul; Tor, Yin Sim; Foo, Jhi Biau.

Afiliación

Loh JS; School of Pharmacy, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor, Malaysia.
Rahim NA; Department of Clinical Pharmacy & Pharmacy Practice, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, Malaysia.
Tor YS; School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor, Malaysia.
Foo JB; Centre for Drug Discovery and Molecular Pharmacology (CDDMP), Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Selangor, Malaysia.

Cell Biochem Funct ; 40(4): 403-416, 2022 Jun.

Article en En | MEDLINE | ID: mdl-35485606

Asunto(s)

Neoplasias de la Mama; Complejo de la Endopetidasa Proteasomal; Apoptosis; Autofagia; Beclina-1/metabolismo; Beclina-1/farmacología; Neoplasias de la Mama/tratamiento farmacológico; Línea Celular Tumoral; Proliferación Celular; Doxorrubicina/farmacología; Femenino; Humanos; Hidroxicloroquina/farmacología; Ubiquitinas

Palabras clave

autophagy; breast cancer; chemoresistance; drug combination; ubiquitin-proteasome system

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Complejo de la Endopetidasa Proteasomal Límite: Female / Humans Idioma: En Revista: Cell Biochem Funct Año: 2022 Tipo del documento: Article País de afiliación: Malasia

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